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Genetic Biomakers of Lung Cancer and Eric Lefkofsky

Both genetic and ecological risk factors influence the advancement of lung cancer. Smoking tobacco is the most prominent ecological risk aspect associated with lung cancer. A recent study conducted by Dartmouth research group has indicated that gene-smoking connections play a vital part in the etiology of lung cancer. In their research, variations in the DNA, or three novel single-nucleotide polymorphisms (SNPs) that trigger the vulnerability of developing the disease, were spotted in the contact analysis, in addition to one SNP for squamous cell lung cancer risk and two SNPs for non-small cell lung cancer risk.

While this research was limited to a particular Caucasian population and the outcome may not be comprehensive to other ethnic groups due to the various genetic backgrounds, the research group intends to test the spotted interaction effect further using other populations’ genotype. Dr. Yafang Li, the leader of the team, says that the limited connection between replication genotype and discovery genotype may have downgraded the influence in the validation study. He continues to state that they believe that as more genotype data develops in the future, they will be in a position to discover more significant gene-smoking interrelations in lung cancer disease.

Eric Lefkofsky is one of the tech figures and influential entrepreneurs in Chicago. Eric is the founder of Groupon and Tempus, his newest venture. Tempus is a technology startup whose objective is to create a foundation to enhance cancer treatment. Having obtained 70 million dollars in funding recently, Tempus has assisted Chicago to go beyond its yearly funding amounts for both 2015 and 2016. Founded recently in 2015, Lefkofsky has subsequently developed to a 200-people firm, and it has succeeded to the top ten tech startups in Chicago.

The burden of cancer on the society has become extensive enough such that almost everybody is related or knows someone who has suffered from the disease. Per se, any developments in cure and treatment effort are significant. Moreover, data on the treatment of cancer patients lack optimal storage. The data storage is in the form of lab test results, remissions, diagnosis, exacerbations and doctor’s notes. This form of storage brings a disconnection between the data collected and its utilization in the growth of efficient customized treatments.

Tempus shares its ranking with some companies such as Outcome Health, a healthcare tech, IRI, a market research firm that offers clients retail, shopper, consumer market analysis and intelligence, Avant, a private firm in the financial tech industry. Other companies in the category include SMS Assist, a cloud-based platform that assists customers in reducing the maintenance costs of properties, and Analyte Health, a company that assists patients to obtain and appreciate healthcare information as confidentially, cost-effectively and conveniently as possible.

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